The Eagles blew a late lead as they fell to the Los Angeles Rams, 24-20, Sunday for their second consecutive loss. Now, the 2-2 Birds will prepare to travel to London to take on their Week 5 opponent, the Jacksonville Jaguars.

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From the Eagles’ chances this weekend to updates on their Super Bowl odds, here’s what the oddsmakers are saying at two of the biggest sportsbooks …

Eagles-Jaguars odds

Despite a 10-point lead heading into halftime, the Eagles were held scoreless in the second half, and allowed the Rams to score 14 unanswered points on the way to their second loss of the season. They also have a ton of unanswered injury questions, including Saquon Barkley and Quinyon Mitchell, both of whom left Sunday’s loss and didn’t return.

Meanwhile, the Jaguars (3-1) are coming off two straight wins — a 35-6 rout of the New England Patriots, followed by a 22-17 victory over the Cincinnati Bengals — and have the best point differential (plus-51) in the AFC.

Now, the two teams will travel to London for their Week 5 matchup. They last played each other in November 2024, when the Eagles defeated the Jaguars at home in a game that is remembered more for one specific play (Saquon Barkley’s iconic backward hurdle) than the actual result (a 28-23 Eagles’ win).

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As they prepare to meet again Sunday, the Eagles enter the neutral-site matchup as 5.5-point underdogs at both FanDuel and DraftKings, marking the second straight week in which they’re underdogs, something that hasn’t happened since 2023.

FanDuel

  1. Spread: Eagles +5.5 (-105); Jaguars -5.5 (-115)

  2. Moneyline: Eagles (+205); Jaguars (-250)

  3. Total: Over 42.5 (-115); Under 42.5 (-105)

DraftKings

  1. Spread: Eagles +5.5 (-108); Jaguars -5.5 (-112)

  2. Moneyline: Eagles (+195); Jaguars (-238)

  3. Total: Over 42.5 (-118); Under 42.5 (-102)

NFC odds update

At DraftKings, the Eagles’ odds of winning the NFC have fallen again following the team’s loss to the Rams. They now trail the Detroit Lions and Minnesota Vikings with the seventh-best odds.

DraftKings

This week
Last week
49ers
This week
+355
Last week
+400
Rams
This week
+380
Last week
+400
Seahawks
This week
+455
Last week
+470
Bears
This week
+850
Last week
—
Vikings
This week
+920
Last week
+870
Lions
This week
+1325
Last week
+970
Eagles
This week
+1350
Last week
+920

Super Bowl odds

The Eagles’ Super Bowl odds have also fallen at both sportsbooks after dropping two straight, and they’re now below their Week 5 opponent as well. The Rams and Buffalo Bills still top the list as early Super Bowl favorites.

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FanDuel

This week
Last week
Rams
This week
+600
Last week
+650
Bills
This week
+750
Last week
+650
Ravens
This week
+800
Last week
+950
Seahawks
This week
+850
Last week
+1000
49ers
This week
+950
Last week
+1000
Chiefs
This week
+1100
Last week
+1100
Jaguars
This week
+1400
Last week
—
…
This week
Last week
Eagles
This week
+2500
Last week
+1700

DraftKings

This week
Last week
Rams
This week
+650
Last week
+670
Bills
This week
+750
Last week
+670
49ers
This week
+850
Last week
+900
Ravens
This week
+850
Last week
+900
Seahawks
This week
+950
Last week
+1000
Chiefs
This week
+950
Last week
+1050
Jaguars
This week
+1500
Last week
—
…
This week
Last week
Eagles
This week
+2400
Last week
+1700

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